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Исследования

Burden of disease of Primary Sclerosing Cholangitis

19. ноября 2024

A Retrospective Cohort Study in Germany

Primary Sclerosing Cholangitis (PSC) is a rare cholestatic liver disease characterized by inflammation and scarring (fibrosis) of the intra- and extrahepatic bile ducts.
A retrospective cohort study utilized German claims data from the Statutory Health Insurance (SHI) database in order to investigate prevalence, incidence, treatment as well as burden and costs of PSC in Germany.

Key results:

  • The prevalence rate of PSC is 0.013% (95% CI: 0.011% – 0.014%).
  • In comparison to the control group, PSC patients show a significantly higher risk of developing conditions such as liver fibrosis and carcinoma.
  • The PSC patients' costs were around 17 times higher than in the control group.
  • This study highlights the healthcare burden of PSC, including serious comorbidities and the prevalent use of off-label drugs, underscoring the urgency for optimized care strategies.

Please find more details in the study poster presented at this year’s ISPOR Europe Congress in Barcelona, Spain.

20241021__Dr_Falk_Pharma_PSC_ISPOR_Poster_v03

Download posterPDF